SAA1 Primary Antibody

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Description

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Feb 2016]

Product Overview
Entrez GenelD
6288
Aliases
SAA; PIG4; SAA2; TP53I4
Clone#
1A12E5
Host / Isotype
Mouse / Mouse IgG1
Immunogen
Purified recombinant fragment of human SAA1 (AA: 19-212) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200-1/1000
FCM (Flow Cytometry)
1/200-1/400
ELISA
1/10000
References
1.Inflammation. 2019 Aug;42(4):1413-1425. 2.Medicine (Baltimore). 2018 Dec;97(49):e13394.
Product Image
ELISA
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
WESTERN BLOT
Figure 2: Western blot analysis using SAA1 mAb against human SAA1 (AA: 19-212) recombinant protein. (Expected MW is 37.6 kDa)
Figure 2: Western blot analysis using SAA1 mAb against human SAA1 (AA: 19-212) recombinant protein. (Expected MW is 37.6 kDa)
WESTERN BLOT
Figure 3: Western blot analysis using SAA1 mAb against HEK293 (1) and SAA1 (AA: 19-212)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Western blot analysis using SAA1 mAb against HEK293 (1) and SAA1 (AA: 19-212)-hIgGFc transfected HEK293 (2) cell lysate.
FLOW CYTOMETRY
Figure 4: Flow cytometric analysis of HepG2 cells using SAA1 mouse mAb (green) and negative control (red).
Figure 4: Flow cytometric analysis of HepG2 cells using SAA1 mouse mAb (green) and negative control (red).
IMMUNOHISTOCHEMISTRY
Figure 5: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using SAA1 mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using SAA1 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.

Catalog#: 31884

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