LPA Primary Antibody

Item Information

Catalog #

Size

Price

Description

LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation.

Product Overview

Entrez GenelD

4018

Aliases

LP; AK38; APOA; LPA

Clone#

8F6A9

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of LPA (4330-4521) expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ELISA

1/10000

References

1. J Stroke Cerebrovasc Dis. 2007 Sep-Oct;16(5):220-4.
2. Clin Chim Acta. 2008 Jan;387(1-2):109-12.

Product Image

Western Blot

Figure 1: Western blot analysis using LPA mouse mAb against truncated LPA-His recombinant protein (1) and truncated Trx-LPA(aa4330-4521) recombinant protein (2).

Immunohistochemical analysis