ITGB4 Primary Antibody
Item Information
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Size
Price
Description
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Product Overview
Entrez GenelD
3691
Aliases
CD104
Clone#
10B10D5
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.PLoS One. 2012;7(4):e32060.
2.J Cell Biochem. 2010 Jun 1;110(3):718-24.
2.J Cell Biochem. 2010 Jun 1;110(3):718-24.
Product Image
Western Blot
Figure 1: Western blot analysis using ITGB4 mAb against human ITGB4 recombinant protein. (Expected MW is 24 kDa)
Flow cytometric
Figure 3: Flow cytometric analysis of A549 cells using ITGB4 mouse mAb (green) and negative control (purple).
For Research Use Only. Not for use in diagnostic procedures.