EphA1 Primary Antibody
Item Information
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Price
Description
EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.
Product Overview
Entrez GenelD
2041
Aliases
EPH; EPHT; EPHT1
Clone#
5D2
Species Reactivity
Human
Immunogen
Purified recombinant fragment of EphA1 expressed in E. Coli.
Formulation
Purified antibody in PBS containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Shannon L. Duffy, Kirsten A. Steiner, Patrick P.L. Tam Gene Expr Patterns. 2006 Feb 6.
2. Elena B. Pasquale. Nat Rev Mol Cell Biol.2005 Jun; 6(6): 462-75.
2. Elena B. Pasquale. Nat Rev Mol Cell Biol.2005 Jun; 6(6): 462-75.
Product Image
Western Blot
Figure 1: Western blot analysis using EphA1 mouse mAb against A549 (1) and Hela (2) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using EphA1 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.