Mouse Monoclonal Antibody to CD298
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
![Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/66b425e24d1b48357bbbcccac582a4c1f3f6b5a8b01c1f949838c1b53e6382e7.jpg?v=1666705287)
![Figure 2:Western blot analysis using CD298 mAb against human CD298 (AA: extra 57-279) recombinant protein. (Expected MW is 51 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/8e42528b280de19fecbbf417db01ff310393fa7c958820d4f45a887cd44c725c.jpg?v=1666705287)
![Figure 3:Western blot analysis using CD298 mAb against HEK293-6e (1) and CD298 (AA: extra 57-279)-hIgGFc transfected HEK293-6e (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/8235be5676310242acf3133503646dec69650e03000dd30c7fe177089d93eef7.jpg?v=1666705287)
![Figure 4:Flow cytometric analysis of THP-1 cells using CD298 mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/6954874a390d26a576fe777d32436b8b3565f38d61af8818a4ca46eac9b9418a.jpg?v=1666705287)
![Figure 5:Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CD298 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/217e865468132de9239a6aac79b641859b12de4b2886fa54be2ec09f1f734ecc.jpg?v=1666705287)
![Figure 6:Immunohistochemical analysis of paraffin-embedded stomach tissues using CD298 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/fb0ec8a9dd4c8f52008ad1b927ad9cffaae84a3c8d2f4009d3d6792239bb4fa8.jpg?v=1666705287)