Humanized CD19 CAR-T cells (CD19 scFv-TM-CD28-CD3z)

Item Information
Catalog #
Size
Price
PM-CAR1042
1x10^6 cells
$1322.0
PM-CAR1042
2x10^6 cells
$1994.0
PM-CAR1042
5x10^6 cells
$3306.0
PM-CAR1042
1x10^7 cells
$5301.0
Description

CD19 is a type I membrane protein expressed by all B cells and B cell precursors but not by plasma cells or other cell types. CD19 functions as part of the B cell antigen receptor complex, allowing B cells to respond to foreign antigens. CD19 is also expressed on all B cell malignancies and is a favorable target for immunotherapy because of its specificity; patients receive immunoglobulin injections because their own B cells are depleted along with the malignant cells.

 

 

ProMab's PM-CAR1042 primary human CAR-T cells express an anti-CD19 CAR containing a humanized CD19-specific scFv, hinge and transmembrane domains, the CD28 costimulatory domain and the CD3zeta activation domain. The CAR-T cells are generated by transducing activated human T cells with replication-defective lentivirus encoding the CAR. After expansion, the cells are cryopreserved and shipped in vials containing up to 10 million cells. Please inquire for orders over 10 million cells. All ProMab cells are guaranteed to be sterile, pathogen-free and mycoplasma-free.

Product Overview
Cell Type Tested
T cells
Formulation
CS10 CryoStor Medium (Sigma Aldrich, Cat, #C2874)
Cell Viability
>90%
Mycoplasma Testing
The cells have been screened using a PCR-based mycoplasma detection kit to confirm the absence of mycoplasma species.
Storage
liquid nitrogen
Shipping & Handing
This product will be shipped in a box containing dry ice at a temperature of -70°C.
For Research Use Only. Not for use in diagnostic procedures.

Catalog#: PM-CAR1042

Price: $1,322.00
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