CD19scFv-TF-TM28-CD28-CD3z
Item Information
Catalog #
Size
Price
Description
ProMab's PM-CAR1048 primary human CAR-T cells express an anti-CD19 CAR containing a CD19-specific scFv, a TF tag, hinge and transmembrane domains, the CD28 costimulatory domain and the CD3zeta activation domain.
Product Overview
Cell Type Tested
T cells
Formulation
CS10 CryoStor Medium (Sigma Aldrich, Cat, #C2874)
Cell Viability
>90%
Mycoplasma Testing
The cells has been screened using a PCR-based mycoplasma detection kit to conirm the absence of mycoplasma species.
Storage
-80°C; liquid nitrogen
Shipping & Handing
This product will be shipped in a box containing dry ice at a temperature of -70°C.
Product Image
CAR Structure
Figure 1. Schematic representation of the scFv, costimulatory domain, and activation domain of PM-CAR1048. This construct targets CD19.
FACS
Figure 2. Detection of CD19-Beam2 CD19 with Beam-2 antibody available from Promab by FACS.
RTCA
Figure 3. CD19-Beam2-28-CAR-T cells kill Hela-CD19-Beam2 positive cells.
RTCA
Figure 4. CD19-Beam2-28-CAR-T cells kill Raji-CD19 19-positive lymphoma cells.
For Research Use Only. Not for use in diagnostic procedures.